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The latest research pointed out that irisin is derived from its precursor protein fibronectin type III domain-containing protein 5 (FNDC5), which can be released from various tissues such as skeletal muscle, fat, and pancreas, mainly involved in the transformation of WAT to BAT, thereby increasing the body’s energy expenditure
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Strom SP, Hossain WA, Grigorian M, Li M, Fierro J, Scaringe W, et al
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